Clinical study of neoplastic thyroid swellings

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Clinical study of neoplastic thyroid swellings

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Title: Clinical study of neoplastic thyroid swellings
Author: Wani, Khurshid Alam; G.H Mustafa; Wani, Rauf Ahmad; Zahur Hussain; Arif, S.H; Malik, Ajaz Ahmad; Choudhary, Nisar A.
Abstract: The prospective study of 108 patients of thyroid malignancy were studied with regard to surgical management in SKIMS, Srinagar. Thyroidmalignancy constituted 0.12%of total hospital admissions. It was seenmainly in patients belonging to rural areas (66.67%).The commonest observed thyroidmalignancywas papillary carcinoma (48.15%), followed by follicular carcinoma (37.04%), anaplastic carcinoma (7.41%), medullary carcinoma (5.55%) and malignant lymphoma (1.85%). Femaleswere affectedmore commonlywith a female tomale ration of 3.1:1.Patients ranged in age from 8 years to 70 years. Maximum number of cases with papillary carcinoma (34.62%), follicular carcinoma (40%) and anaplastic carcinoma (66.67%) presented in 4th, 5th and 6th decades of life respectivelywith a mean age of 34.85 years, 42.40 years and 61.25 years for papillary, follicular and anaplastic carcinoma respectively. Swelling in front of neckwas themost common (96.29%) presenting symptom, followed by hoarseness of voice. The majority of patients were having hard swellings with nodular surfaces and the swelling were free.No patient had retrosternal extension of thyroid swelling. 18.51% of patients had clinically palpable lymph nodes. Fine needle aspiration cytology was an important adjuvant to pre-operative diagnosis having sensitivity of 92.59%and specificity of 100%.Thyroid scan detected cold nodule/nodules inmaximumnumber (90.74%) of patients. Indirect laryngoscopy detected vocal cord palsy in 14.81% patients pre-operatively. Total thyroidectomy was performed in maximum (83.33%) number of patients followed by near total thyroidectomy. The main post-operative complications were hypoparathyroidism (12.96%) and recurrent laryngeal nerve palsy (11.11%). Anaplastic carcinoma was found a rapidlygrowing tumour,with a limited surgical scope.
URI: http://dspaces.uok.edu.in/handle/1/67
Date: 2007-01


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